Optimmune® Ophthalmic Ointment

Features and Benefits: The only FDA-approved veterinary cyclosporine ophthalmic product. Achieves therapeutic effect while avoiding systemic toxicity. Sterile, preservative-free formulation reduces the chance of secondary infection and chemical irritation. Shelf life up to 24 months with no refrigeration.

An ophthalmic ointment containing 0.2% cyclosporine for management of chronic keratoconjunctivitis sicca (KCS) and chronic superficial keratitis (CSK) in dogs.

Pharmaceutical Name:

0.2% Cyclosporine, USP Ophthalmic Ointment

OPTIMMUNE Ophthalmic Ointment is indicated for management of chronic keratoconjunctivitis sicca (KCS) and chronic superficial keratitis (CSK) in dogs.

Dosage and Administration: 

• Remove debris with suitable nonirritating solutions. Apply a 1/4 inch strip of ointment to the affected eye(s) every 12 hours. The ointment may be placed directly on the cornea or into the conjunctival sac.

It is recommended that dogs exhibiting chronic recurring conjunctivitis be tested for adequate tear production to determine if they are suffering from early stages of chronic KCS.

For best results in treating KCS, cyclosporine ophthalmic ointment should be administered early in the course of the disease before irreversible damage to the lacrimal tissue, or dense corneal scarring or pigmentation occurs.

Dogs afflicted with KCS or CSK will most likely require lifelong consistent therapy (see EFFICACY section). For CSK, because environmental factors such as ultraviolet (UV) radiation are implicated in the pathogenesis, clinical signs may subside in the winter months when light intensity is reduced or if the dog is moved to a lower altitude, or indoors, and thus exposed to less UV radiation.

In cases refractory to cyclosporine, the diagnosis should be reevaluated and a different course of therapy considered. Periodic reassessment of the need for OPTIMMUNE^® Ophthalmic Ointment therapy is recommended.

Supplied:

• 6 x 3.5g tube

Active Ingredients:

• Cyclosporine, 0.2%

Fair Balance:

For ophthalmic use in dogs only. The safety of OPTIMMUNE^® has not been determined in cases of preexisting viral or fungal ocular infections, nor in puppies, pregnant bitches, or dogs used for breeding. In clinical trials, ocular and periocular inflammatory reactions, transient hyperemia, epiphora, mild discomfort of the eye and mild alopecia were reported in a small number of treated dogs.

For additional information, please see the product label.

Important Product Information:

Do not use Optimmune in cases of pre-existing viral or fungal eye infections. Treatment should be delayed until the viral or fungal infection has been successfully treated. Keep out of reach of children.